Posted by : Selva Friday, July 23, 2021

 


Stoneman syndrome or fibrodysplastic ossificans progressiva (FOP) or Munchmeyer's disease is a rare genetic disease of ectopic soft tissue calcification with hand and foot deformities leading to severe restriction of joint movements. It was first described in 1692 in a young patient who turned into wood. It may be sporadic or autosomal dominant. The disease is caused by mutation in the bone morphogenic protein (BMP) type I (Activin A receptor, type I [ACVR1]) leading to dysregulated bone formation.The incidence, as reported from Europe and United States, is around 1 in two million individuals. 









Leave a Reply

Thanks for Reading

Subscribe to Posts | Subscribe to Comments

Welcome to My Blog

Popular Post

Blogger templates

Need our help to upload or customize this blogger template? Contact me with details about the theme customization you need.

Recent

Contributors

Members

Search This Blog

- Copyright © King's of Radiology -Robotic Notes- Powered by Blogger - Designed by Johanes Djogan -